In the pharmaceutical industry, all products must be of the highest quality in order to ensure the least risk to patients, and the products must be guaranteed to meet certain standards.
Liquid chromatography is an analytical technique used to separate a particular sample into its components. The most common form of liquid chromatography used today is high-performance liquid chromatography (HPLC), which pumps the sample mixture through the column at high pressure.
Results from the separation, quantification and identification of components in a mixture by HPLC analysis can be used to quantitatively and qualitatively analyze finished pharmaceutical products and their ingredients during the manufacturing process.HPLC analysis is one of the most common techniques used to elucidate the structure and quantify impurities in pharmaceutical formulations and to measure the quality of the drug substance.
This technique is particularly suitable for compounds that are not easily volatile, thermally unstable and have high molecular weights