Potentiometric analyses are performed by measuring the potential of an electrochemical cell under static conditions. When no current is passing through the electrochemical cell, or when a negligible current is present, the composition remains unchanged. Today, ion concentrations can be determined by directly measuring the electrode potential using potentiometric methods. These electrodes allow for the rapid quantitative determination of a large number of ions without introducing significant interference. Therefore, potentiometry is a useful quantitative method. Potentiometric titration is also frequently used in the quantitative analysis of active ingredients and excipients in pharmaceutical products. One of the advantages of this method is that there is no chemical indication resulting from measuring the electric potential on the material. Another advantage is that it can be performed with small amounts of the desired sample.