Transdermal/Franz diffusion cell systems are used in the pharmaceutical and cosmetic fields for epidermal use of creams, ointments and gels in the form of cosmetics, moisturizers, analgesics, etc.products applied for epidermal use in pharmaceutical and cosmetic fields.
In vitro release tests are performed to determine the kinetic factors of release in Franz Diffusion Cells, as they affect the release profile of formulations as well as the effect of the physicochemical properties of the active pharmaceutical compound in the drug product.
In vitro release tests are performed to determine the kinetic factors of release in Franz Diffusion Cells, as they affect the release profile of formulations as well as the effect of the physicochemical properties of the active pharmaceutical compound in the drug product.
Additionally, these systems are used for toxicity assessment and quality control compliance in pharmaceutical drug products.
Transdermal/franz diffusion cell systems has advantages;
- Less processing of tissues,
- The absence of continuous sample collection and
- A small amount of drug is required for analysis
These are among the advantages.
Membrane selection is a critical step in permeability studies performed using Franz cell systems because generic membranes can provide data on significant changes associated with the size of the drug being evaluated and the system used for its dissolution.
In our laboratory, in order to make accurate and effective evaluations, in vitro release studies are carried out in drug forms such as creams, gels, lotions, ointments, etc. with our Franz Diffusion Cell system in accordance with the current USP <1724> monograph.